that引导的定语从句不可以修饰整个句子。
因为如果that引导的定语从句修饰整个句子，那么定语从句就是非限制性定语从句，而that只能引导限制性定语从句，不能引导非限制性定语从句。
that引导的定语从句只能修饰名词或代词，关系代词that可作主语或宾语。例句：
(限制性定语从句)
1.A plane is a machine that can fly.
2.The book (that/which/省略) I bought yesterday is very interesting.
(非限制性定语从句)例句：
1.China is a big country with a long history, as is known to all.
2.Tom was late for school again, which made his teacher angry.
